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Multimodal Analgesia After Cardiac Surgery

Content Type: Protocols | Provider

Created: June 28, 2021
Contributors: Kathryn Deere, PharmD, BCPS • ERAS Cardiac Collaborative Network
Editor(s): Cheryl Crisafi, MSN, RN, CNL • Amanda Rea, DNP, CRNP, AGACNP-BC, CCRN, CMC, CSC, E-AEC • Gina McConnell, RN, BSN, CCRN • Shannon Crotwell, RN, BSN, CCRN • Alexander Gregory, MD, FRCPC

Summary

Multimodal analgesia is a key component of enhanced recovery after cardiac surgery and has been associated with improved pain control, reduced opioid exposure, and support for postoperative recovery. This approach integrates multiple pharmacologic and nonpharmacologic strategies that target different pain pathways, allowing for individualized pain management while minimizing reliance on high-dose single-agent therapy.

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AI Assistance Statement

This summary was developed with assistance from artificial intelligence and reviewed, edited, and approved by the listed editor(s). Reference: OpenAI (2025). ChatGPT (November version) [Large language model]. 
https://chat.openai.com

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The Virtual Education Center (VEC) and all included content are intended to inform ERAS Cardiac Members on a wide range of topics related to enhanced recovery. The information presented has been provided by enhanced recovery experts and is for educational purposes only.

It is not intended to describe, recommend, or suggest any specific medical practice or intervention, nor should it be considered formal medical advice or consultation. The ERAS Cardiac Society cannot guarantee that the information provided is accurate or complete in every respect. Therefore, the Society is not responsible for any errors, omissions, or clinical outcomes resulting from application of the information obtained through the VEC.

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